Don’t be limited 
by qPCR or dPCR.

Countable PCR gives you true quantitation with unrivaled sensitivity, faster results, and lower cost than dPCR — all with the simplicity of a qPCR assay.

Countable PCR redefines what's possible.

Digital PCR (dPCR) promised you absolute quantification and multiplex assays.

But in reality, dPCR only delivers statistical estimates, and developing assays takes months.

So, you fall back on qPCR because it’s easier to use — and you think the data is good enough.

Countable PCR will change how you feel about PCR.

Highest
sensitivity
Highest
precision
Broadest
dynamic range
Out-of-the-box
multiplex success
Real-time,
automated results
Lowest
project cost

See how Countable PCR outperforms legacy PCR methods.

Quantitative PCR
Digital PCR or Droplet Digital PCR
Countable PCR
Quantification
Quantitative PCR
Relative 
Inferred via Ct values
Digital PCR or Droplet Digital PCR
“Absolute”
Estimated via Poisson statistics
Countable PCR
True
Direct single molecule counting
Unbiased counts
Sensitivity / LoD
Quantitative PCR
Limited
Typically >1% MAF
Digital PCR or Droplet Digital PCR
High, with effort
About 0.03% MAF
Countable PCR
Highest
0.004% MAF
10x better
Reproducibility / 
Precision
Quantitative PCR
Low
50%-100% CV
Digital PCR or Droplet Digital PCR
Moderate
10% CV
Countable PCR
High
1% CV
10x better
Dynamic range
Quantitative PCR
Broad
Digital PCR or Droplet Digital PCR
Narrow
Countable PCR
Broad
5x higher
Assay development
for multiplexing
Quantitative PCR
6-18 Months
Requires custom probes, extensive optimization, prone to interference and PCR bias
Digital PCR or Droplet Digital PCR
3-12 Months
Requires custom probes, careful signal balancing to minimize rain
Countable PCR
Instant
No custom probes required, no signal balancing
10x faster
Data analysis
Quantitative PCR
Manual, subjective
Ct thresholding
Digital PCR or Droplet Digital PCR
Manual, subjective
Poisson thresholding
Countable PCR
Automated, objective
Real-time, direct
Instant results
Project cost 
(materials, labor, time)
Quantitative PCR
Moderate
Digital PCR or Droplet Digital PCR
Highest
Countable PCR
Lowest
3x lower

Validated in the real world.

Clinical diagnostics

With ~30M compartments, the Countable PCR platform provides significantly higher sensitivity with fewer reactions in our oncology assays and opens new opportunities in the fields of NIPT and infectious disease. The workflow is easy, with potential for automation, and delivers highly precise results.

Tricia Zwiefelhofer
Director of R&D, LabCorp
Rare event detection

For hosts with this infection, there is a greater than millionfold difference in parasite load, the Countable Labs method ‘covers this range with a single DNA input…this is an extremely important need that is not being met by any other technology.’

Rick Tarleton
Professor, University of Georgia
in an interview with Genomeweb
Cell & gene therapy

I’ve been working in the cell and gene therapy (CGT) field for a long time… In the past, ddPCR was the only viable option. But now, with Countable PCR, we have a solution that delivers ultra-high sensitivity — with 30 million partitions and an incredible 99.9% sample recovery rate (compared to ddPCR’s 70–80% and just 20–30K partitions). It’s also easy to use and has a short run time.

Robert Lou
CTO, Carrigent
Cell & gene therapy CRO

Get a closer look at Countable PCR.

We're now Countable Labs but some publications use our former name Enumerix. Also, our technology is Countable PCR, formerly UltraPCR.

01

"Using a 4-color optical setup, we demonstrate that we can incorporate 10 different fluorescent dyes in the same [reaction]"

bioRXiv

Janice H. Lai, et al. 2023.

Read publication
01

"Single template separation ... can aid high-order multiplexing assay designs to achieve NGS-like precision DNA counting"

ACS

Eleen Y. Shum, et al. 2022

Read publication
01

“This approach exhibits improved accuracy over existing dPCR platforms and enables a greatly increased dynamic range…”

PNAS

Peiyu Liao, et al. 2020

Read publication

Connect with a specialist to learn how Countable PCR transforms your workflow.