Get the highest sensitivity genomics platform.
Whether you’re discovering critical biomarkers or delivering products patients trust, Countable PCR makes it possible.
Achieve unmatched sensitivity and reproducibility.
Deliver results with absolute confidence when you get true quantification with zero bias and no sample loss. Best of all, achieve it all with scalable workflows that lower cost without compromises.
The difference is Countable.
30 million compartments
Get true isolation of single molecules for direct target quantification. Count exactly what’s in your reaction. No estimation, no subjective thresholds.
No PCR bias
With 30 million compartments and true single-molecule isolation, get clean signal that enables instant, easy multiplexing.
No sample loss
Analyze 100% of your input. With a broad dynamic range to count up to 1 million targets and sample tolerance up to 35 µL or 1 µg, find the rarest events in one reaction.
The performance is Countable.
30 in 1,000,000
Targets detected
6-log
Dynamic range
<1%
CVs
Up to 1,000,000
targets counted per reaction
0%
Dead volume
1-35 µL
INPUT RANGE
Up to 5kb
amplicons
Instant
multiplexing
* Available on Countable 10. Contact us for service projects today.
Unlock results that were out of reach.
Get high-quality results, designed for GMP workflow
Objective & automated – no manual thresholding, every run analyzed with built-in ID Score quality metrics
Reproducible & transferable – <1%CV, simplify assay validation and transfer smoothly to production
Audit-ready – software includes secure records, audit trails, user-login and features that support 21 CFR Part 11 compliance
Multiplex instantly, without the cross-talk
Isolate every molecule – true single-molecule partitioning means every target behaves as if single-plex, for bias-free amplification
Eliminate probe balancing – no cross-talk or bleed-through across channels, so multiplex experiments work the first time
Accelerate assay development – Universal Multiplex kit delivers faster turnaround for probes, at lower cost
Find out how Countable PCR technology works.
Learn more
Whatever you measure, measure it with Countable.
Therapeutic QC
Multiplexed viral titer and genome integrity
Vector copy number
Gene editing efficiency
Biodistribution studies
Contamination detection
Rare Event Detection
Minimal residual disease tracking
Low frequency variants (SNP, indel, CNV)
Rare isoform
Somatic mutation
Rare pathogens
Orthogonal Validation
Gene expression
Splice isoform profiling
Variant/mutant allele frequency quantification
Structural or copy number variation
Quantify unconventional DNA/RNA
Compatible sample types
Cell free DNA
Tissue DNA
FFPE DNA
RNA
cDNA
Plasmids
Nucleosomal DNA
Genomic DNA, digested
Genomic DNA, sheared
Genomic DNA, undigested
Crude cell lysate
Virus with capsids
Viral DNA
Viral RNA
Key specifications.
Performance
Total detectable dynamic range
6 logs (1 to 1,000,000 molecules)
Limit of detection (LoD)
As low as 0.004% MAF*
Reproducibility (%CV)
<1% across replicates
Channels available for detection
4
*Experiment-dependent
Sample processing
Partitioning method
Centrifugation into gel matrix
Number of compartments
Approximately 30 million per reaction (tube)
Reaction volume (per tube)
50 µL
up to 35 µL input DNA
Sample loss / dead volume
0%
Fluorescent chemistry supported
Universal Multiplexing, TaqMan, or combined
Fluorophores
Up to 4 channels per reaction
Ch01 - FAM, Alexa488, Atto488
Ch02 - HEX, VIC, Atto532
Ch03 - TEX615, Atto590
Ch04 - Cy5, Atto647N
Data processing
Detection method
Laser lightsheet 3D imaging
Throughput
96 reactions per run
Scan time
40 seconds per reaction
Time to results
~5 hours for 4 channels x 96 reactions, shorter if fewer channels and sample number
Data analysis
Direct counting, fully automated
Data output
CSV, HTML reports + ID score for per-channel QC
21 CFR Part 11 support
Included in software