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Detecting rare events takes more than qPCR or dPCR can offer – how Countable PCR sees them
If rare event detection feels like searching for 40 molecules in a million — that’s because it is.
Whether you're tracking somatic mutations, oncogenic strains, or infectious disease, you need sharper tools. Traditional tools like qPCR and dPCR hit their limit around 0.01%. That’s solid — but not enough when early signals mean better patient outcomes.
Countable PCR was built for this exact challenge.
With a true single-molecule counting system and a simple PCR workflow, it delivers unmatched sensitivity — without the trade-offs.
See what others miss
0.004% VAF in one experiment
Detect 1 to 10⁶ targets — rare and common — in the same reaction. This means saying goodbye to sample dilutions and endless replicates.
Get insights from every drop of your sample – in a single reaction
35 µL input. 0 µL lost.
When you can load up to 35 µL per reaction, hyperwelling is no longer needed. The best part? Not a drop is lost to dead volume. Run your sample once — and analyze all of it.
Count with certainty
No Poisson corrections. No thresholds.
Every DNA molecule is isolated into its own compartment within a 3D matrix before it’s amplified and counted directly. This true quantification removes the need for statistical estimation or subjective thresholding.
Get more accurate measurements, fast
Interrogate rare and common targets in the same reaction
Compare all your biomarkers side-by-side. Run up to 4-plex panels using standard hydrolysis probes or Countable’s Universal Multiplexing chemistry to get sensitive and direct comparisons, quickly.
Remove data analysis complexity
No specialized analysts needed.
Countable PCR gives direct counts, eliminating the need for bioinformatics experts. Reduce your operational complexity and time to results.
Ready to detect the rarest targets?
Countable PCR was designed from the ground up for rare event detection researchers.
It offers far better sensitivity – and is simple and cost-effective enough for scale.
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