Highly sensitive detection of complex KMT2A rearrangements with a single PCR assay

Highly sensitive detection of complex KMT2A rearrangements with a single PCR assay

Direct RNA counting of 18 fusion transcripts across six common KMT2A fusion partners

The Ancora KMT2A-r Assay detects and directly quantifies 18 fusion transcripts across six common KMT2A fusion partners in a two-tube multiplex workflow. The assay calls a fusion only when it detects both the KMT2A and partner sequences on the same RNA molecule. 

On the Countable PCR platform, direct counting lets researchers quantify the same fusion marker across time points without per-run standard curves. Calculated limits of detection ranged from 0.0007% to 0.001% across the six fusion partners at one million ABL1 reference copies.

Download the product sheet for the full target list, analytical performance data, RNA input requirements, and bundle ordering information.

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